WEEI>On Demand>>MFB: Dr. Mark Kieran, Director, Pediatric Neuro-Oncology Center, Dana-Farber

MFB: Dr. Mark Kieran, Director, Pediatric Neuro-Oncology Center, Dana-Farber

Aug 19, 2014|

Dr. Kieran spoke about specific treatment options for brain tumor patients that are available now that were not curable 10 years ago. Though rare, brain tumors are the most common form of solid tumors among children under the age of 15 and represent about 20% of all childhood cancers.

Transcript - will not be 100% accurate

Peace he said WEEI special broadcast. It's the thirteenth annual WEEI -- and Jimmy Fund radio telethon presented by our ballot insurance foundation. No broadcasting from Fenway Park here's a rumor -- Christian Fauria and team then -- Monthly support provides dependable funding for groundbreaking cancer research and compassionate patient care at Dana Farber Cancer Institute help us recruit 61 of the month -- donors by 2 PM please call. 877738. 1234. Or go online to Jimmy Fund dot org and join Jimmy's team monthly. And -- giving program right now. Tim -- liberal -- Christian Lorie with you middays with and -- -- the second hour of our portion of the radio telethon presented by our bella insurance. And we've already talked about the patriots connections -- Jimmy Fund with Christian and the Boston Red Sox connection. With -- Maloney. Already mixed in some basketball and just will be at Steve Pagliuca the Boston Celtics co owners can join us shortly and we've got to get to some hockey -- and what better way to do that with doctor mark here and from the Dana Farber Cancer Institute. Not directly with the Bruins percentages that would -- or ask. We're going north of the border with you right did you really start off -- but still hot dogs and maple leaf gardens. When I was a counties to sell ice cream and Coco it was the perfect job for Euro because you're not allowed to so during the game only during the intermission. So basically is a child you're forced to watch the game in between. -- -- -- -- -- -- And it is worth while classmate and watch -- game it was rough but it's still I'm -- -- doubled to open but he still played -- you know it's the perky and pretty busy travel keeps me busy so. And my wife these British didn't want to get playing hockey so unfortunately it's mostly gone from the them a lot of. I don't need to reinforce how the hockey community embraces cancer that's pretty well known hockey circles and I've seen firsthand before I came here work with penguins Mario -- his foundation but. In your experience working with the Dana Farber Cancer Institute can you speak to how the teams have integrated themselves and raised awareness for the funds that are needed to put forth the research. That you do it DS yeah. He has you know it's this really takes an entire community it's not just patients and doctors it's everything around it it. Patients need help when they need help -- often where you don't know where to go. And sports athletes sports clubs such a prominent role now in our society. And in you know we give them a lot of flak for that kind of salaries they make and stuff but in many ways there an important clues that bring society together. And allows us to focus on some of the important issues and as you said without the Red Sox and patriots the Bruins and Celtics and many other organizations. Many of the fundraisers and such that that we rely on it wouldn't happen. You know docked -- one of the reasons why we do this telephone obviously to raise money to allow people like yourself and others to to take -- to new levels each and every year so. In the last decade or so this is always amazed new talks on the doctors and say you know when they talk about the treatments to kids are going through or adults are going to receipt could this have happened ten years ago. And usually the answer is no we've come a long way. How far have we come -- Britain brain tumors in the treatments for like debt in the last ten years. So astronomical it's almost like a new world that ten years ago we knew very little about even what caused two were what made brain tumors -- so to speak. To bring -- unfortunately have the honor of being the most common cause of cancer related death that children -- the most common -- but it's the most malignant it is difficult to treat. Not surprisingly because you have to be very careful about not damaging the brain or -- treating so there's a kind of double edged sword there that we have to be very cognizant of what's really happened in the last ten years is as we have started to understand the underlying causes of brain cancer and have been able to develop a number of drugs that target those. I'm ideas that he didn't even exist five years ago we're now routinely using in the clinic. So that we don't treat brain tumors we treat this child's to -- based on the particular mutations of that tumor. And we're seeing dramatic responses in how wide array of different tumor types. You know we seagulls athletes write your goal is always there. Hillary win the World Series or Super Bowl as a doctor does that excite you do you see that go ahead do you see we know where you -- five years ago where we could be five years from now even. Absolutely but I I think it's you know it's not going to be a day where we wake up one day on the headlines of the newspapers you know cure for cancer found yet there are many types of brain tumors now for which we -- already a 100% of the patients we party made that program -- Obviously the question is for those were curing. We have to do so with less toxicity so that they've really become normal the rest of their lives and for those that were not curing those are where we need to. Continue to press on the research to make the difference. But it's important for people to understand that it the battle doesn't start today looking forward. We birdie made enormous progress and we're curing in fact the majority of kids. About 6065%. Of all kids with a brain -- now our long term cured of their disease. That's unacceptable for the 35% that we happen to touch yet. And certainly the 65% bear a lot of scars and damage to get them to be cured and we have to improve that as well. But I think -- obviously -- an -- you have to be somewhat of an optimist as well moving forward and I'm pretty excited about where we're going. -- talk on the treatment end of the funding. That is generated today. Does that help you pinpoint. You know -- based on the age of each kid that determines what type a specific treatment they would get. How do you get to that point where you know OK here's Kate who's ten and under as opposed to a kid who's fifteen and under how does that how do you is there -- way to. Generally pinpoint exactly what treatment should go for what's which age group. So it's actually not based so much on -- anymore it's actually based on the molecular underpinning of your -- America. So there may well be a five year old and a fifteen year old they get exactly the same -- be. And a ten year old in between whose tumor has a slightly different set of mutation that now gets a different therapy. So it's somewhat less -- -- the one issue of course it's important for each is that as the brain is developing some of the treatments that are very effective. Will damage a young child much more than an older child. And -- those circumstances you may have to pull back a little bit in order to protect the cognitive abilities. Of that child and look for other therapies and in that sense there's a bit of an H component more for molecular component you put all together and optimize care. So many of those treatments in so much of this progress has been made in the last few years because people like you donating so please do donate to the Jimmy Fund right now like going to www. Jimmy Fund dot org or. WEEI. Dot com slash Jimmy Fund. And light up that our ballots hope wars where. Coming close -- -- 185000. Dollars in funds raised. Already doctor Karen thanks so much for joining us and pistol to -- this year and if that it at least that's not considered competition for Boston. I want to ask about sports you can comes in a little bit later on thanks so much for coming on good senior thank you.

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