Aug 19, 2014|
Just before his 40th birthday, Larry was diagnosed with non-Hodgkin's lymphoma. He has experienced the Jimmy Fund/Red Sox partnership from both sides - as a patient and as a part of the Red Sox. Larry is also on the Dana-Farber Board of Trustees, and currently serves as the chair of the Trustee Development Committee. Dr. Nadler was Larry's physician. He spoke about how cancer care has changed in the last decade, and how Dana-Farber will influence change in the next 10 years.
Transcript - will not be 100% accurate
-- 148128. Dollars with about 35 minutes to go in the first portion of the first day of the WB pianist Jimmy -- radio telethon live from Fenway -- -- got -- -- I got a couple of big -- -- you know coming in -- Michael Roberto from -- the -- -- 15100 dollars and Ian -- Winchester. 15100 dollars thing QE and as far as I know nobody has yet to top the first donation today. Which was our pot pal Johnny Miller who handed me a check for 101000 dollars this morning. When the doors open so again we thank -- for his continued. Generosity. I said Jerry earlier and -- -- to -- to -- with the dais that is the one day of the year. That Larry it's nice to us and we are nice that Larry that's exactly -- the president the CEO of the Boston Red Sox Larry Lucchino. And doctor Lee Nadler senior vice president experimental medicine and medical oncologist at the Dana Farber welcome -- a year since we've been nice to each other. He doesn't it actually does not seem like that is going by so quickly but I'm glad he started that way. Because. It is -- guide them. The best way to two experiences that -- is now on I think I've radio because the eighty's that you guys so compelling. I must commend you missed the one day when when I think you guys do get it he. And now and it ended is that empathy that you bring these stories and if you wanna be inspired. The all day in day in the morning you guys. Before we get two year old story which we've heard exactly. You wanna say what year was -- Treated ran into this young guy was like a hundred years ago at the break we're talking about Tom Moore of course you didn't hear rush yesterday but we -- and we would have supported homeowners candidacy. For commissioner if we knew his platform going -- With Honda through nick a finalist calm afterwards in the hat he was hitting all the right notes at all the best ideas let me tell -- -- before him. Well I I think that the the problem is that the process when -- went by so quickly and Tom made his decision now after people came to him and -- to us to consider. He made his decision. Eight million in mid July to Jesus and so it was kind of hard to. To like get all the platforms out that quickly but he did have a very Cogent and appealing presentation which is what got to to the final round. The question now is will. And now rob Manfred -- -- going to be able to -- to develop a consensus. This is necessary to implement some of these things. It's easier to come up with the ideas than it is to implement the ideas. But I think at Tommy's determined to press forward and not revolutionary change because they're not there's a lot of things simple common sense items to. But the and well. I think that gave him the benefit of this product project seniors processes that. Which we elevated the conversation -- elevated conversation there's now only greater eagerness and willingness it is to fight for some. These changes you know what I thought was it was simplistic and beautiful in its simplicity was the fact that he made the analogy that you wouldn't make the movie that was three and a half -- -- and we're expecting people watch a baseball game that -- three and a half hours long and me the other this second good point. The people were leaving in the seventh and eighth inning which is when the drama and the climax should be really keeping you in your seats. Exactly and and that I don't have any questions the pace of the game in the length of the game's going to be addressed I would say in the next year do certainly before. The next to -- BA because the players association has to be partners with us in this effort to reform. One more baseball question win at the owners' meetings ideas come up with Justin Bieber simple one when somebody said in force the pitch clock or automatic. Passed ball on the on the intentional walk right to a bunch of people stand up wooden -- don't do that we can't do that we haven't had those kind of substantive conversations. At the league meaning on the things they've been more moralists are handled by committees that's a problem that is why not it is a problem I think that's the benefit of of Tom's. Insurgency -- candidacy. He eight EP practicing the forefront do you think Tennessee a lot more debate discussion and I hope implementation. Just don't eliminate the pitching coaches trip to them on a love note that it stands. So dramatic favorite part of the game -- won the Davis blocks out -- -- -- that guy from and -- name is from Tampa that again only him and all can now they want to go to the -- love them to read lips and to participate. But taping some of those if you have one again or something like them two when -- -- Q would you like to know with the pitching collapses. That's a good idea yeah he wants the wire yet coaches and players like the NFL in -- unlikeliest take clay hurry the hell up yes I have like this throw strikes. I have had to keep it down in the zone and I know I know. And -- sent doctor -- that now at least Nadler senior vice president of senior vice president experimental medicine and medical oncologist when you must have a really big business card to get all that on how -- What what's what's that what's happened in the year that we've since we've last spoken. Sized hail marry Detroit this is it really extraordinary here. Back when I first or Larry -- top -- taking -- we had just drugs to educate intravenously because side effect yeah. And then when Larry didn't go intermission we did a transplant which was very difficult to leave here I describe it as a sledge -- But in 2014. The world just changed and I think it's unbelievable this is the lymphoma diesel common. Took drugs get approved guess what people who go to transplant taking pills. And win these three drugs that are pills get approved until Larry that this is a real chance that will cure the disease with a bunch of pills. And that'll be yet you won't even have to be in the hospital. You won't have to really have your blood counts affected it will be no major side effects. And this is weird science -- that's what you're supporting today. It took twenty years and brilliant people all over the world to come up at this Dana -- did a lot of this. But it together all the building blocks ended up with a revolution 2004 teams -- bad a year. And I say one thing about that it was have been a year because you had. World class scientists researchers physicians working on this. But they get their fresh ideas from the -- dollars come in -- and -- the system. And for those of you out there listening this fuel and -- changes like the dramatic changes that are currently NAFTA talking about now. You've got to make contributions this that this this goes to. World changing kind of research in an insult to you know -- product your boss. This proves popular dissent your your tiny once again was crappy right now I -- yeah outside here at this out of the thinking that if you -- foot -- for the -- at a time when a farewell no you sent a telegram to document and you go and covered wagon drove. All the right what year was that -- -- senators have that there's 1894. Others don't go wagon and 1985. From that date to this and all this was a big here but from forty years ago. How many years ago now to what he had twenty years when he eight years ago to today how much as the treatment for lymphoma for example to. Huge absolutely hugely went from nonspecific. And not hearing a lot to tearing anymore without taxes does one thing that Larry's it's so important so very important. Would change from when I was young and -- Larry. It was enough money in the system especially in the government system. To take young guys like me and support me but it dollars average reduced -- -- funded debt went three out when it went. And the young kids the young guys because I made my really important discoveries I was in my thirties that made the difference Larry. When he was just 48 at me. And we can't let those young people. Not you know fall out of the system so -- generation. So that dollars are a million times is important today as they -- in those days. Makes a lot of sense tell tell me on a scale from like one to five what the most important I'm sorry what the most expensive aspect of this kind of researches. Is -- the personnel salaries is -- the the that the the clinical stuff that you have to do is that the cash teams that custom and not -- live her best tennis what what's the most expensive aspect what we're talking about here. Support people via supporting young people. Through those years when they can't get government support it's the people on the people who work for them. You know I was working up with Larry. I'm just ahead fifteen people working for me you know can afford wouldn't fibers it's real and if you don't have an army it's like this weekend. I'm going to play a baseball game with six guys. You're not gonna win a game and and and no bench none at all until the Red Sox what was but -- site. This kind of day this that day like today after -- your odds of survival. I was told. That I added three intentions. Really. And what did you think. -- when you go that they can't hear a common numbers that can't hear it -- -- and that I was reassured that would say yes that had been the history. Now. We talked about it a lot right but that was number news and wounding. What would be the number today -- and then look for that disease. Well he was one of those patients who didn't go intermission on the first time so. Maybe five at ten to make it. But the differences he -- He would have gotten into remission the first time the drug was toxic took another 30% we discovered that I'll let it tech at number 30% of people. To cure. So I don't think Larry would have ever seen a transplant I think he would've gone through mission and that would have been it and this is true not just with lymphoma. Lee and I were talking earlier about -- -- mother of one of our. Front office people. The Red Sox. Was diagnosed recently with lung cancer and it's a very miserable very tough disease. We thought that this is to there was a long tough. Road ahead in that there may be. Down the road but. Right now there is a pill leave it there is available when and why why was -- -- Larry's wisdom doesn't matter what time today and except upon close maintenance act so this woman was coming from San Diego to Boston. It to visit and so we asked our doctors who always come through and I was on vacation. Monday he saw the patient just cleared a spot. He sat down and said you know if we can't look at it genetic mutation if you have this -- -- -- growth factor percent to mutation that -- You can take -- pill instead of getting chemotherapy and not get response. And so I read you know Larry I read a note she's a brilliant woman she wrote doubted she said Atlantis is Sunday at last night. I -- my first film and I promise you that this time next year she could still be taken well. She got the -- -- that the -- him I think. A final very brief question and and it's the sort of I'd like cliche go to question two researchers and Smart people like you they only asked once today. You said so what just happened in 2014. Was there literally and hop. Moment in the -- this year off or was it like that day in and week and then two weeks three weeks and finally just evolves into here's the solution or was there -- -- a moment. There are. So so comes from my life but not my own work. -- 2000 and what was the first time that they use the 23 2013 2000 foot. When they could take your own immune system tweak it and it can't disappear. Drugs to an end to people and the body's other drugs. That had their own immune system fight back. And those of the breakthroughs of the future so the very first time we can have your own body kill your own cancer. That's an aha moment for me well. Doctor -- medley -- never thank you very much for your time good to -- again Larry always a pleasure talking BS thank you to the for what you do today and thank you guys that he is truly our pleasure at 8777381234. A -- 25 bucks can provide patients with subsidized parking and taxi vouchers. Giving them better access to care and even more importantly peace of mind during treatment help us reach our goal. Of 750. By the end of this program that's about twenty minutes from now and -- now to support our patients and our families.